Bella le Pard's career as a TV presenter is 'on hold'. To fill her days, she sits in a coffee shop and obsesses about a wedding dress in the neighbouring shop. Her luck changes when she gets the call from her old boss at 'Flair for living TV' to present a pilot for a new food and chat show. But her revived TV career is short-lived when one of the celebrity guests threatens to steal the show. Bella finds herself turning to blackmail to save her job. But will her threat to reveal her boss's infidelity keep her on TV? And will she ever find a reason to buy that dream wedding dress?
The Big Day - A person's wedding is the most important day of their lives, for in that day two souls join as one. That is the one day that gives two persons the Totality, Independence, and the All-Encompassing Righto stay permanently with each other, forever. It is the one day of beautiful and most powerful magic that blesses and binds two unique souls in holy matrimony from that day till the end of time. Your wedding day should be the most joyous day of your life. It is a big event that marks the start of your lives together; and to make it a memorable one, Proper Planning, Budgeting, Organizing, Backup Plans and a strong team for effective Execution are of critical importance in ensuring everything works. Everything starts with Wedding Planning. So what's Wedding Planning? This book is all about Wedding Planning; an all-encompassing concept and essentially it simply means that you plan for everything that should occur on your wedding day and you also plan to prevent everything that should not occur. On top of that you should also plan to mitigate if undesirable things do happen on that day. There are many factors to consider, from the concept or theme of your wedding to the guests to be invited and so on, and each of these play its own unique role in making sure the overall event turns out as desired. This book will help you to know all the necessary things you need to know to have a successful wedding of your dreams.
The aim of this book is to illustrate the big opportunity to transfer computational techniques, well accepted and used in medicinal chemistry to food science; through this, we hope to discover new pollutants, possible dangerous food additives, contaminants from industries, xenoestrogens, etc. The paradigm is: if a molecule can interact with a receptor (i.e. a Nuclear Receptor), it can modify the signaling pathway and should be investigated to discover negative effects on food. The interaction can be predicted using in silico techniques well known by medicinal chemists to discover new lead compounds or to study the behavior of a protein ligand interaction. The book starts with an introduction about the computational methods applied to food safety by authors coming from a big food company, who elucidate the importance of this approach for industries and food agencies. In Chapter Two, the authors give an overview of in vivo tests for food contaminant and toxin evaluation. In Chapter Three, in vitro and in silico models of digestion are compared. In Chapter Four, the authors, belonging both to an in silico lab and a wet lab use a case study of poliphenols to show how to merge in silico prediction and in vitro controls to gain time and money in estrogen receptors. Additionally, poliphenol binding studies use a molecule modeling approach. In Chapter Five, a non-typical docking approach is presented: a reverse docking approach. Chapter Six and Seven introduce the problem of receptor flexibility and how to treat this important characteristic that must be considered in computational simulations. Chapter Eight is a review about QSAR methods well considered in this approach. Chapter Nine show a non-conventional informatics approach to ab initio in silico protein structure prediction. The last chapter is dedicated to the informatics requirements for in silico simulations to help researchers approaching this field.
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